Spirit Molecule - Psilocybin Molecule

[3-(2-Dimethylaminoethyl)-1H-indol-4-yl] dihydrogen phosphate – C12H17N2O4P

Welcome to the Spirit Molecule Cultivation Guide. Here you will learn what you need to know to begin cultivating your own edible mushrooms and psychedelic mushrooms, if you live in a country in which doing so, is legal. You will find a list of all the supplies you will need, as well as for instructions on how to get started.

Pleaste note: Growing Psilocybin containing mushrooms for consumption is a conceivably illegal action in some countries, we do not support or condone illegal activities in countries where the law does not prohibit. This guide is for those who live in countries where growing Psilocybin mushrooms is legal, as well as for those who wish to carry out the operation regardless, with the intention of providing educated advice in order to reduce the risk of harm.

A 115000 person Global Drug Survey carried out in 2017 found that the least harmful psychedelic compound to be Psilocybin (Magic Mushrooms). The Economists Daily Chart also has Psilocybin listed as the least harmful drug, with Alcohol ranking the highest.


Psychedelics have been defamed since the early 1970s for various reasons, mainly related to politics, but in recent years the views around psilocybin (magic mushrooms) have grown more tolerant. These days more and more people are eager to learn to grow magic mushrooms at home. Home cultivation provides a reliable, continuous supply of mushrooms and eliminates any risk associated with buying from unknown sources or picking in the wild.

Learning to grow your own mushrooms can also be a challenging and fun experience, which could quickly grow into a full-time hobby for many who embark down this road.

There are 2 methods of growing psilocybin mushrooms that will be covered in this guide, these include growing using a Psilocybin Grow Kit and Growing from Scratch using the PF-Tek Method. The PF-Tek method is your classic indoor mushroom cultivation technique. Like anything, it can be a little tricky to get a hang of, but once you understand the method, its fairly easy to bring in a good harvest of caps and it can work out extremely cheap, which is a bonus. Best of all, it utilizes things that you can get from any supermarket or horticulture store.

Growing mushrooms can be a challenging experience and you may have some failures before you are able to successfully grow your first batch. We will guide you through everything you need to know for a successful first grow. If you are not confident enough to start a full grow from scratch yet, you can try one of our Grow Kits to get your feet wet before you dive deep. Our Grow Kits are fully sterile and have a higher success rate than growing from scratch, especially for beginners.


As a beginner, it might be a scary thought to begin a full grow operation from scratch without any prior experience. Growing Mushrooms can be challenging and we have all faced problems during the process. A good place to start before you take the plunge is using a grow kit to grow your first batch of mushrooms. This will give you an idea of how mushrooms grow, what they like, what they don’t like and will give you a hang of the basics.

Grow kits are relatively easy to use, but like everything else, there are some issues with contamination if you are not careful.

Our grow kits are relatively self-explanatory and easy to use. We provide full instructions within the kits and also online in our Guides section of the website. If you have purchased one of our grow kits simply refer to the guide provided in your kit and begin your grow, everything you need to learn is included in the guides.


As a beginner, it might be a scary thought to begin a full grow operation from scratch without any prior experience. Growing Mushrooms can be challenging and we have all faced problems during the process. A good place to start before you take the plunge is using a grow kit to grow your first batch of mushrooms to familiarise yourself with the process before diving deep.

In this guide, we will take you through the process of growing your own mushrooms using the PF-Tek method. The PF-Tek method is your classic indoor mushroom cultivation technique. Like anything, it can be a little tricky to get a hang of, but once you understand the method, its fairly easy to bring in a good harvest of caps and it can work out extremely cheap, which is a bonus. Best of all, it utilizes things that you can get from any supermarket or horticulture store.

We will cover everything you need to get started, including a list of supplies you will need how to build a grow box, fruiting chamber and tips on how to store your mushrooms after you have harvested your first batch.


To start your home grow operation you will need to gather a few items. A lot of them you can find here in our store, everything else you can find in your local department store or on eBay if you prefer to shop online. Once you have gathered all the necessary supplies you’re ready to move on to the next step.

Tip: The ingredients mentioned below are enough for 1 jar, with a 400ml capacity. If you are making more (or smaller) jars you can adjust the ingredients accordingly.

  • 4 Wide Mouth half-pint Mason Jars with Lids
  • Measuring Cup
  • Hammer and a Small Nail
  • Large Mixing Bowl with Spoon
  • Strainer
  • Heavy Duty Foil
  • Pressure Cooker
  • 50 – 100L Plastic Storage Box
  • Spray Bottle
  • Glove Box (optional but highly recommended)


Once you have gathered all the necessary supplies and prepared your cleanroom and/or glove box you are ready to begin. We have divided the grow in to 5 steps you should follow in order. Its worth having a read through the whole process once fully before beginning your grow operation. The steps in this process are as follows:

Spirit Molecule Psilocybin Mushroom Cultivation Guide - 5 Steps to Growing Magic Mushrooms


Once you are ready to start go to Step 1, good luck on your grow operation and remember, the most important thing is to ENJOY yourself!



Separate the Jar lids and using a small hammer and nail, punch 4 holes around the circular jar lid, evenly spaced out. Once ready, fully wash your jar and lid and let them dry. While you wait for them to dry move on to the next step and prepare your substrate.


The amounts given here are for 1 jar with a capacity of 400ml. You should adjust these amounts if your jar is a different size. Here is your basic PF-Tek recipe:

In a large mixing bowl measure out your 120ml of vermiculite. Add 1 teaspoon of instant coffee to 55g of Filtered or Distilled water and mix thoroughly until all the coffee is dissolved. Slowly add the coffee mixture to the virmiculte and stir until all of the water is absorbed and all of the virmiculite is fully coated and wet.

Now add in the 60g of Brown Rice flour slowly into the mixture and mix until it is fully mixed in with the wet vermiculite. Now add in 1 teaspoon of Gypsum and stir fully.

Your substrate is now ready. Take your jar(s) and fill each one with your substrate. Don’t fill your jar all the way to the top, you want to fill it up to the rim under the lid (half-inch of the rim). Sterilize the top half-inch of the jar using alcohol rubs and then top off the jars with a layer of dry vermiculite. Now place the jar lid on put your jar aside while you prepare the rest.

Tip: When mixing your materials, be sure to mix the water and vermiculite before you add in everything else. This ensures that everything else sticks nicely to the wet vermiculite rather than making one big mess.


Sterilization is the process that uses high temperatures and pressurized steam to kill off any biological contaminants that might be hanging around your substrate. By heating your sample to 250F (121C) at a pressure of 15 PSI for 20 minutes, you can effectively kill off any competing molds, bacteria or fungi – leaving all of your substrate for your magic mushroom culture to thrive on.

You are now ready to sterilize your jars with steam. Tightly screw on the lids and cover the jar with standard kitchen tin foil. Tightly secure the foil around the jar to stop any condensation getting into your jar during the sterilization process.

Place a folded kitchen towel into your pressure cooker and add enough water into the pot to sit slightly below the top of the towel. Then place your jars securely on top of the towel. The towel is used to stop water splashing up in and on to your jars. We don’t want to directly cook the jars but allow the steam from the vaporizing water to sterilize our jars.

Secure your pressure cooker and heat for 20 minutes at 15 PSI. Once your pressure reaches 15 PSI start the timer for 20 minutes. It won’t do any harm if you choose to sterilize slightly longer but you must sterilize for a minimum of 20 minutes.

Once your jars have been fully sterilized, remove the pressure cooker off the heat and release any remaining steam inside the cooker by pulling the release valve. Never open the pressure cooker before you have released all the pressure inside. Let your jars cool down for a few hours inside the pressure cooker before moving on to the next step. Your jars must reach room temperature before you begin inoculation, this is very important. Do not open the pressure cooker lid until you are ready to begin inoculation, you want to avoid contaminating the jars as much as possible.

Safety Tip: If you are unfamiliar with using a pressure cooker please take some time to study it online. Pressure cookers can be extremely dangerous if used incorrectly.


During this step, it is vital that you keep your working area and equipment as sterile as possible to avoid contamination. We recommend you carry out the following step using a Glove Box or a Laminar Flow Hood. For many home growers, the most optimal and cost-effective method is to build a simple glove box. If you do not want to spend the time to build a glove box, ensure your working environment is as clean as possible and free from moving air currents.


If you have purchased your Spore Syringe from our store you would have received a Sterile Syringe. If you are using a sterile syringe you do not need to heat it with your lighter, this step is only if your syringe may not be sterile. Use your lighter to heat the syringe needle until it glows red hot. Allow the needle to cool down and then wipe it using an Alcohol Wipe, make sure you do not touch the needle with your hands.


Shake the syringe to distribute the spores evenly into the solution. Remove the foil from the top of your jars and insert the syringe as far as it will go through the first hole.

Inject about 2cc of the spore solution into the side of the jar, you want to point the needle towards the glass container and inject the spore towards the glass… Repeat this step for each hole, making sure you wipe the needle with alcohol wipes between each injection.

Once you have injected 2cc into each of the 4 holes, cover the holes with Microspore Tape and set the jar aside. You are now ready to move on to Step 3: Colonization. It is recommended you move on to this step immediately and not delay the process.

Tip: Be very careful to avoid contamination during this process. Sterilized Latex Gloves and a Surgical Face Mask are good items to stock up on, however, as mentioned earlier the best option is a still air box or glove box.



    By now you have put in most of the hard work, from this point on you have to let time do its thing.

    Place your jars in a warm, dark place to colonize. We recommend an airing cupboard for this, but anywhere that’s dark will do. Place the jars on a high shelf if possible, as this will keep them away from the contaminants that exist at floor level and get whipped up every time someone walks by. You should keep the ambient room temperature at around 70F (21C), this is the most ideal temperature but you are safe to linger slightly higher or lower.

    Colonization should begin within a few days of inoculation with spores, or within 24 hours if you’re using liquid culture. The first thing you will notice will be the fuzzy white spots appearing on your substrate around the area you injected your spores; these are germinating spores.

    More of these will appear and during the next four weeks, they’ll grow and grow, hopefully exhibiting rhizomorphic growth, which is exactly what we want. As these rhizomorphs grow together, they’ll create a white covering over the entire substrate and will eventually begin to strangle the substrate and pull it away from the sides of the jar. This is perfect, but it can allow space for some moisture to gather on the glass. Don’t worry if this happens; it’s perfectly normal.


    Once the substrate inside your jars is fully colonized, including the bottom of the substrate, give the about another week before removing them from the jars. This allows the mycelium to consolidate, meaning it will move into fruiting more quickly once placed in your grow box.

    Depending on how long you’ve left your jars, you might be able to see the beginnings of the mushrooms fruit snaking their way along the side of the glass; in fact, we recommend waiting until these primordia are showing before transferring your cakes to the grow box. They’ll look like tiny worms with darker coloured spots on the ends, sort of like angry baby eels!

    A rough estimate of how long this period will last is between 4 – 8 weeks. Once your cakes are ready, move on to Step 4: Fruiting.

    Tip: If you see any strange colors or smells, dispose of the jars immediately. Some contaminants are deadly for humans despite what some online debate suggests. Contamination could also spread to other jars, so it is vital you dispose of the jars before they get a chance. If you are unsure what the contamination is, dispose of the jar and do not open it indoors.


    During this stage we will first perform the Dunk & Roll process and while we wait for that to complete its cycle we will prepare our Grow Box. Once everything is in place we will transfer our cakes into our new Grow Box and watch them fruit hundreds of beautiful fungi.


    Gather your jars in the kitchen by the sink. Clean the area you will be working around and fill a large bowl or saucepan, big enough to hold all your cakes, halfway with water, set this aside for now.

    Remove the jar lids and remove the dry vermiculite layer,  lightly tap the sides and back of the jars until the cake comes out. Now gently rinse the cake under cold tap water until it is clean, then place it in the bowl you filled with water earlier. Repeat this step with the remaining jars until all your cakes are in the water.

    You need to submerge the cakes fully underwater, you can achieve this by placing something heavy on top of the cakes to lightly push them underwater. Then cover the bowl with plastic film and place it in the fridge for 24 hours.

    While you wait for your cakes to hydrate for the next 24 hours, you can begin building your grow box.

    Tip: If you are finding it difficult removing the cake from your jar, lightly tap the edge of the jar against a soft book until the cake comes out. 


    Take your plastic storage box and drill ¼ inch holes 2 inches apart all over the box. You want to begin at the bottom and drill evenly going around the whole box, then move up two inches and do the same again. You need to drill holes on all sides, as well as the bottom and the lid. Drill the holes from the inside to avoid cracking. If your box cracks slightly don’t panic, you can tape any cracks later on. Once you have drilled all your holes, begin the next step.

    Before your grow box is ready to host cakes you’ll need to fill it with a few inches of rinsed Perlite to help create the pressure gradient that will draw fresh air into your grow box and ensure good passive ventilation. For this step you will need to wear a Face Mask, as Perlite powder can be harmful to your lungs if inhaled. Empty your bag of perlite into a kitchen strainer and rinse it fully under cold tap water until all the perlite is fully soaked.

    Now empty the wet perlite into your grow box and space it out evenly and flat, you want around 4-5 inches of perlite in your grow box. Cut a square piece of heavy-duty foil the same size as each of your cakes and place these pieces of foil on top of the perlite, evenly spaced out in the grow box. These pieces of foil are what your cakes will sit on. Your grow box is now ready.

    Tip: Sit your grow box over four stable objects to allow airflow underneath, small plastic containers will work great for this. Cover the surface under the box to protect from moisture leakage.


    Once your cakes have hydrated for 24 hours and you have completed putting your grow box together you are ready to begin the next step.

    Measure 1 cup of Fine Vermiculite and spread it out on a piece of kitchen foil. Place the foil in the oven for 20 minutes at 180C. Once the vermiculite is ready, remove it from the oven and place it on top of your workspace. Remove your jars from the fridge and gently rub each cake into your vermiculite to fully coat each side of the cake, including the top and bottom.


    When your cake is fully covered in vermiculite, transfer it into your grow box and place it on top of the foil you prepared earlier. Do this for each one of your cakes. You are now done, all that hard work finally got you to this final stage, all you have to do now is take care of your little beauties and watch the mushrooms grow.


    Once you have transferred your cakes to the grow box, use a spray bottle to mist the inside of the box to create the desired humid environment the mushrooms like, close the lid and place the grow box on a high surface in a room with indirect sunlight.

    You should mist the grow box several times a day, each time you mist you should also fan out the air. Fanning out the air removes the build-up of CO2 inside the grow box, if you don’t fan the box several times a day your mushrooms will struggle to sprout, this step is very important and you should not skip it.

    You should aim to keep the humidity inside the box between 80 to 95%, constantly fan and mist, you can never do this too often, we do this up to 20 times per day.


    It won’t take long for your cakes to start fruiting. As light is a pinning trigger, they should start to pop out from the cakes within a couple of days, sometimes this can take longer depending on the strain. When you begin noticing your mushrooms are popping out, move on to the next step to begin harvesting, at the right time of course.

    Spirit Molecule - Magic Mushrooms


    Congratulations! You have successfully grown your first batch of mushrooms and are ready to pick your rewards. The only thing left now is to pick the fruiting bodies, dry them and store them.

    You know your mushrooms are ready to pick when you notice the veil under the cap breaking open. As soon as you see the first signs of the veil breaking your mushroom is ready and you should pick it before it releases its spores.

    Use a Scalpal to cut the mushroom from the base. If you don’t have Scalpels gently twist the mushroom from the base and pull. This method is not ideal as it can cause the cake to break off with the mushroom, putting a dent in your next flush. Its definitely worth investing in a Scalpal.

    Once you have harvested all of your mushrooms from the first flush you can dunk & roll your cake again for a second flush. The second flush usually gives higher yields than the first flush.

    Tip: You may find that some of your mushrooms wont fully grow and remain as small specs. These are called mutes and are extremely potent, make sure you pick those tiny fella’s!


    Once you have picked your mushrooms your cake is ready for a second flush. Simply follow the Dunk & Roll steps above by soaking your cake for 24 hours and putting it back into the grow box. You do not need to add the vermiculite to the cake for re-flushes, simply dunk for 24 hours and you’re good to go.

    Good luck and have fun!




      Freshly picked mushrooms are over 80% water and will go bad within a few days. To store your mushrooms long term you need to dry them. There are various ways to dry mushrooms, the simplest is to leave them out on a sheet of paper in front of a fan, but this will still leave some moisture, which if not removed properly can spoil your mushrooms.

      Our favourite option is using a dehydrator, these can be picked up relatively cheap these days and are a must for all home growers. If you don’t want to invest in a dehydrator, make sure you fan out as much of the water as you can until your mushrooms are crispy and break easily, you don’t want them to bend when you try to break them if they bend they are too wet.


      Investing in our cultivation course might be a good next step. In the course, we will cover all the basics and also dive into the more advanced techniques not discussed here. The course will include lifetime access to all videos and course materials and you will get unlimited updates as the course grows.

      Sign up above today to be one of the first to get notified when our course goes live and receive a 15% discount on launch day.


      How long does the whole growth process take if I am growing using a Grow Kit?

      The time it takes for you to harvest a good batch of mushrooms can vary depending on many circumstances, but in general, the whole process takes between 4 to 9 weeks.

      How long does the whole growth process take if I am growing from Scratch?

      The time it takes for you to harvest a good batch of mushrooms can vary depending on many circumstances, but in general, the whole process takes between 4 to 9 weeks.

      When are my mushrooms ready for picking?

      Once your cakes begin to sprout, it will generally take between 6 to 13 days for your mushrooms to be ready. The best way to determine whether your mushrooms are ready for harvest is to check the veil under the cap. If the veil has started to separate from the cap your mushroom should be picked.

      Tip: You don’t want to allow the mushroom to release its spores. Once the veil fully breaks off the mushroom will spray its spores all over your tank and this will be a sign for the mycelium to slow down the production of more fruits and can result in lower yields. Pick the mushrooms before the veil fully breaks to be safe.

      Where can I get Mushroom Spores?

      We sell a wide variety of strains right here on the website. Check out the Spore Store for what is available. Our spores come in Syringes, Vials and Prints.

      What is the best grow substrate to begin with?

      The grow tek used in this guide is the well known PF-TEK, which uses Vermiculite and Brown Rice Flour to form the cake for the growth substrate. This is the most common method used by many cultivators and is the perfect method for beginners to start with. Once you familiarise yourself with the PF-TEK you can move on to more advanced grow methods such as Rye Grain.

      What are the best Psilocybe cubensis strain for beginners?

      The easiest substrates for growing your first batch of mushrooms are the popular P. cubensis strains including B+Amazonian and Golden Teachers. More experienced growers may appreciate the challenge of growing the more advanced strains such as the Albino A+.